This formation is actually pretty crazy. I usually prefer gun formations, but this formation worked incredibly well in all four H2H games I played. Some of the most effective adjustments were:
Y Trail: Motion the WR running the slant route to the left. This will put them behind the WR running the deep route, allowing for a disguised receiver.
WR Out: Change the WR on a curl route to a streak. If the user follows the streak, the post will likely be open. If they follow the post, the streak will likely be open. I had Darren Waller at WR running the hot route streak, and he got 200+ yards and 3 touchdowns.
PA X Cross: Change the FB to pass block. This helps defend against blitzes during the play-action, allowing the play to develop. In Cover 2 the post route will be open. In Cover 3 the cross route should be open.