I would think on a pass rusher you'd go with unstoppable force....but would you bother using AP on that same player for edge threat?
On DBs I can see going with universal coverage but you'd probably also want mid or deep KO as abilities.
Now what about on your QB....I have LTD Lamar so I can put escape artist on him...I mean, do you think that would be OP in house rules to have EA always on? You could also put Double me on 2 WRs or on 1 and freight train on your HB
What would you tihnk is the best combo of X factors and abilities to use?